PowerPlex(R) Y23 GMIDX Files Revision History

Original Release (v1.0):  06/2012

Allele sizing and panel ranges based on mean sizing values observed between 31XX and 35XX instrument platforms using POP-4(TM) Polymer
2800M positive control genotype in panel file.

The stutter values included in the PowerPlexY23_Stutter_IDX_v1.0 file for the PowerPlex Y23 System have been determined experimentally. 
Stutter filter based on mean plus 3X standard deviations of observed stutter at each locus.

Plus stutter filters are included for the two trinucleotide repeat loci, DYS481 and DYS392.  

Filters are also included for plus 2 and minus 2 nucleotide stutter associated with the DYS19 locus. 

PowerPlexY23_Panels_IDX_v1.0
PowerPlexY23_Bins_IDX_v1.0
PowerPlexY23_Stutter_IDX_v1.0

Release (v1.1):	11/2012

The stutter distance for DYS438 was modified to reflect that it is a pentanucleotide repeat: From Distance 4.25 and To Distance 5.75.

Release (v1.2):  04/2014

Removed virtual allele 26 for DYS570 and narrowed the panel ranges:
DYS570		from: 76	151 	to	76	150.9
DYS635		from: 151.1	208.2 	to 	151.2	208

Changed the bin width from 0.5 to 0.4 bases on the plus side of DYS481 alleles to allow for consistent allele calls between the 35xx and 31xx instrument platforms. 



Version 2.0 Release:  05/2015
Allele sizing and panel ranges based on mean sizing values observed between 31XX and 35XX instrument platforms using POP-4(TM) Polymer with WEN ILS 500 size standard.

Additional virtual alleles added for following loci:

DYS576: 15.2, 16.1, 16.3, 18.2
DYS389 I: 12.2,12.3,13.2, 18
DYS448: 13,14.4,16.4,18.5,19.5,21.4
DYS389 II: 28.2, 29.2, 29.3, 31.1
DYS19: 20
DYS391: 4, 9.1, 10.2, 12.2
DYS481: 23.1, 24.1, 25.1, 26.1, 27.1, 28.1
DYS549: 11.3
DYS533: 10.2, 11.3, 12.1, 12.3, 13.1, 15.3, 16.3
DYS438: 5, 9.2, 9.4
DYS437: 14.2, 19
DYS570: 15.2, 16.1, 16.2, 17.3
DYS635: 22.3,28.2
DYS390: 21.1, 23.2, 24.1
DYS439: 10.3
DYS643: 9.2, 10.1
DYS393: 6, 19
DYS458: 10.3, 13.2, 14.3, 20.1
DYS385: 6, 9.1
DYS456: 10, 15.1, 18.2, 19.1, 24
YGATAH4: 7, 11.3, 14.1

Removed virtual allele 18 for DYS549

PowerPlexY23_Panels_IDX_v2.0
PowerPlexY23_Bins_IDX_v2.0
PowerPlexY23_Stutter_IDX_v2.0
